A randomized, crossover, open-label study of 291 men who were naive to pharmacologic ED treatments showed that once-daily doses of tadalafil were superior to sildenafil in improving both IIEF-EF and SEP-Q2 and SEP-Q3 scores (Eardley et al 2005). In a Partner's Preference Study, tadalafil was preferred by 79.2% of women compared with 15.6% who preferred sildenafil.